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2010;8:27. 2. Bowyer S, Roettcher P. Pediatric rheumatology clinic populations in the United States: results of a 3 year survey. Pediatric Rheumatology Database Research Group. J Rheumatol. 1996;23:1968–74. 3. Malleson PN, Fung MY, Rosenberg AM. The incidence of pediatric rheumatic diseases: results from the Canadian Pediatric Rheumatology Association Disease Registry. J Rheumatol. 1996;23:1981–7. 4. Symmons DP, Jones M, Osborne J, Sills J, Southwood TR, Woo P. Pediatric rheumatology in the United Kingdom: data from the British Pediatric Rheumatology Group National Diagnostic Register.
Initial wrist involvement is rare and may indicate the progression to extended oligoarthritis. Shoulders and hips are almost never involved. Cervical spine disease, while rare, may be manifest by torticollis. Uveitis is rarely a presenting sign. 1 Unilateral arthritis of the left knee in oligoarticular JIA 34 Chapter 3. 2 Posterior view of unilateral arthritis of the left ankle, showing valgus deformity of the hind foot irregular pupil. The anterior uveitis (iridocyclitis or iritis) may be low grade and early inflammation is only detectable by slit lamp examination.
Although all races can be affected, the prevalence is much reduced in non-Caucasians. Girls outnumber boys 4:1. It affects about 60 per 100,000 children. 3 Oligoarthritis 33 Etiology About 70 % of oligoarticular JIA patients have ANA and there is a disproportionate number with the HLA alleles at DRB1*08 locus . Other factors may be at play, giving rise to the predominance of girls. 4 Clinical Manifestations Approximately half of oligoarticular JIA patients will have a single joint involved at onset, mainly the knee (Fig.