Clinical Pain Management: A Practical Guide by Mary E. Lynch, Kenneth D. Craig, Philip W. H. Peng

By Mary E. Lynch, Kenneth D. Craig, Philip W. H. Peng

Scientific soreness administration takes a realistic, interdisciplinary method of the evaluation and administration of ache. Concise template chapters function a brief connection with physicians, anesthetists and neurologists, in addition to different experts, generalists, and trainees dealing with ache. according to the foreign organization for the learn of Pain’s medical curriculum at the subject, this reference presents to-the-point best-practice information in an easy-to-follow structure together with tables, bullets, algorithms and instructions.

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2003) Central sensitization and LTP: do pain and memory share similar mechanisms? Trends Neurosci 26:696–705. 21 Miraucourt LS, Dallel R, Voisin DL. (2007) Glycine inhibitory dysfunction turns touch into pain through PKCgamma interneurons. PLoS One 2:e116. 22 Moore KA, Kohno T, Karchewski LA et al. (2002) Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord. J Neurosci 22:6724–31. 23 Harvey RJ, Depner UB, Wassle H et al.

G. CPSP 1 year after surgery). The idea that pain is in some way etched into the CNS has been at the heart of efforts to halt the transition to chronicity by blocking noxious perioperative impulses from reaching the CNS using a preventive pharmacological approach. g. the peripheral nociceptive barrage associated with surgery, central sensitization) is a causal risk factor for CPSP. However, if the relationship between acute postoperative pain and CPSP is merely correlative, and both are caused by one or more factors that themselves are inter-related, then no type or amount of blocking will prevent the development of CPSP (Figure 1, bottom panel).

Psychosocial factors Research has only recently begun to examine psychosocial risk factors associated with the development of CPSP. Several risk factors CPSP or CPSP disability have been identified, including heightened preoperative state anxiety; greater preoperative catastrophizing; higher concurrent emotional numbing (a symptom of post-traumatic stress) at 6 and 12 months after thoracotomy; fear of surgery; an introverted personality; and “psychic 35 Clinical Pain Management: A Practical Guide vulnerability”; a construct similar to neuroticism.

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