Cation Flux Across Biomembranes by Yasuo Mukohata

By Yasuo Mukohata

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Taguchi and Miss Y. Matsumura for their skilful cooperation to the purification of the enzyme. REFERENCES 1. D. (1975). Ann. Rev. Physiol. 37:13. 2. C. (1957). Biochim. Biophys. Acta 23:394. 3. C. (1960). Biochim. Biophys. Acta 42:6. 4. , Gache, C. and Lazdunski, M. (1978). Eur. J. Biochem. 85:561. 5. , Fahn, S. J. (1963). Proc. Natl. Acad. Sei. A. 50:474. 6. K. S. (1965). J. Biol. Chem. 240:1473. 7. , Hegyvary, C. and Kume,S. (1972). J. Biol. Chem. 247:6530. 8. J. (1966). J. Biol. Chem. 241:1882.

Rev. Physiol. 37:13-55. , and Schwartz, W. (1978). J. Gen. Physiol. 72:409-442. L. (1975a). Q. Rev. Biophys. 7:239-274. W. (1978). Biochim. Biophys. Acta 527:115-130. M. (1978a) Biochim. Biophys. Acta 525:230-251. M. (1978b) Biochim. Biophys. Acta 525:252-264. J. (1972) In "Role of Membranes in Secretory Processes" (L. ), pp. 182-202. North Holland, Amsterdam. F. (1978). Scientific American 239:92-125. L. (1977). In "Biochemistry of Membrane Transport" FEBS Symposium No. 42 (G. Semenza and E. ) pp.

Lane, L. , and Schwartz, A. (1976). J_. Biol. Chem. 215, 4794-4795. 2. , and Matsui, H. (1977). 3rd Annual Meeting of Japan Bioenerg. Group, Tokyo, 41-43. Fernandes Department of Physiology Institute of Biomedical Sciences University of Sao Paulo Sao Paulo, Brazil The intimate nature of the mechanism involved in the Na transport across amphibian skins is still deeply controvertial particularly regarding the Na-K coupling at pump level in the basolateral membrane of the epithelial cells. Transient alterations of 42 K unidirectional fluxes across the isolated short-circuited skins have been shown to be a powerful tool in the study of Na and K movements across the tissue and their relationships (Varanda and Lacaz-Vieira,1979).

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