By David J. Stott, Gordon D. O. Lowe
Written through prime specialists within the box, Cardiovascular illnesses and future health within the Older sufferer covers the epidemiology, pathophysiology and administration of heart problems within the older sufferer. in line with and accelerated from the cardiovascular part in Pathy's rules and perform of Geriatric Medicine, 5th variation, this booklet offers authoritative, useful info on one of many significant ailments of previous age. an exceptional reference for scientific and pre-clinical degrees, it is a must-have source for geriatricians, cardiologists, and GPs, in addition to cardiac professional nurses and complicated perform nurses.
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Extra info for Cardiovascular Disease and Health in the Older Patient: Expanded from 'Pathy's Principles and Practice of Geriatric Medicine, Fifth Edition'
16 Biochemical changes with age have been reported including alterations in sarcoplasmic reticulum and Ca2+ uptake across membranes. 17 These biochemical alterations result in prolongation of isovolumetric relaxation. These changes may be of functional importance, particularly with regard to reduced diastolic function and cardiac failure with preserved ejection fraction. Changes in cardiac physiology with ageing Healthy ageing is associated with little change in systolic function or cardiac output at rest.
Autonomic control of the ageing heart. Neuromol Med 2008;10:179–86. 21 Ferrari AU, Radaelli A and Centola M. Physiology of ageing:Ageing and the cardiovascular system. J Appl Physiol 2003;95:2591–7. 22 Elveback L and Lie JT. Continued high incidence of coronary artery disease at autopsy in Olmsted County, Minnesota 1950 to 1979. Circulation 1984;70:345–9. 23 Wenger NK. Cardiovascular disease in the elderly. Curr Probl Cardiol 1992;17:609–90. 24 Di Angelantonio E, De Castro S, Toni D et al. Determinants of plasma levels of brain natriuretic peptide after acute ischemic stroke or TIA.
2013 John Wiley & Sons, Ltd. Published 2013 by John Wiley & Sons, Ltd. 1 Changes in cardiovascular system with healthy ageing. 3 – 5 This hypertrophy is caused mainly by increased impedance to left ventricular ejection due to reduction in elasticity and compliance of the aorta and large arteries with resultant higher systolic arterial pressures; age-related degenerative aortic valve disease with sclerosis and thickening of valve leaﬂets and proximal bulging of the interventricular septum may also contribute; however, the contribution of these changes to LVH has not been deﬁnitively proven.