Cardiovascular Diabetology: Clinical, Metabolic and by E.Z. Fisman, A. Tenenbaum, J.S. Borer

By E.Z. Fisman, A. Tenenbaum, J.S. Borer

The superiority of weight problems, metabolic syndrome and diabetes - 3 hyperlinks of a similar >atherothrombotic chain' - has reached pandemic proportions world wide. consequently, our civilization is at warfare opposed to a threatening enemy: cardio-diabetes. a number of autonomous physiological procedures underlie the clustering of cardio-diabetes, together with important weight problems, insulin resistance, dyslipidemia, irritation, impaired glucose tolerance, and high blood pressure. Early detection is of overwhelming significance for public overall healthiness. The complicated and intimate dating among heart problems and diabetes from easy technology to medical and healing matters is mentioned during this awesome booklet. starting with molecular, biochemical, inflammatory and mobile facets, this ebook maintains with histological and pathophysiological concerns, information specific difficulties in particular metabolic and scientific settings, and eventually analyzes numerous points of medical pharmacology targeting the optimum administration of mixed dyslipidemia and non-insulin antidiabetic remedy in cardiac diabetic sufferers. This e-book might be a achieve in wisdom for each heart specialist, diabetologist, professional in inner medication, nutritionalist, normal health practitioner and scientific scholar.

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Janeway CA Jr, Medzhitov R: Innate immune recognition. Annu Rev Immunol 2002;20:197–216. Leitinger N: Oxidized phospholipids as modulators of inflammation in atherosclerosis. Curr Opin Lipid 2003;14:421–430. Li D, Mehta JL: Antisense to LOX-1 inhibits oxidized LDL-mediated up-regulation of monocyte chemoatractant protein-1 and monocyte adhesion to human coronary artery endothelial cells. Circulation 2000;101:2889–2895. Tsimikas S, Witztum JL: Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk.

Yuan SY, Ustinova EE, Wu MH, Tinsley JH, Xu W, Korompai FL, Taulman AC: Protein kinase C activation contributes to microvascular barrier dysfunction in the heart at early stages of diabetes. Circ Res 2000;87:412–417. Beckman JA, Creager MA, Libby P: Diabetes and atherosclerosis: epidemiology, pathophysiology, and management. JAMA 2002;287:2570–2581. Kolm-Litty V, Sauer U, Nerlich A, Lehmann R, Schleicher ED: High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells.

Janeway CA Jr, Medzhitov R: Innate immune recognition. Annu Rev Immunol 2002;20:197–216. Leitinger N: Oxidized phospholipids as modulators of inflammation in atherosclerosis. Curr Opin Lipid 2003;14:421–430. Li D, Mehta JL: Antisense to LOX-1 inhibits oxidized LDL-mediated up-regulation of monocyte chemoatractant protein-1 and monocyte adhesion to human coronary artery endothelial cells. Circulation 2000;101:2889–2895. Tsimikas S, Witztum JL: Measuring circulating oxidized low-density lipoprotein to evaluate coronary risk.

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