Brain Signal Transduction and Memory by Masao Ito

By Masao Ito

Mind sign Transduction and Memory

summary: mind sign Transduction and reminiscence

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If this was the case, and the mechanisms suggested in this paper were operative, one may wonder about the way these channels have been considerd so far, and even about the nomenclature (second messenger-operated channels, SMOCs) that we have recently proposed (1). Finally, the nature of Ca2+-storage organelles involved in the generation of [Ca2+]i transients needs to be mentioned. Up to recently, the identification of these organelles was proposed based exclusively on cell fractionation studies, with little interest on the cytological impact of the physiological findings.

Biophys. Res. Commun. 151:973. , and Nishizuka, Y. (1988). Mol. Endocrinol. 2 : 1 0 4 3 . Nishizuka, Y. ( 1 9 8 4 ) . Nature. 3 0 8 : 6 9 3 . Nishizuka, Y. ( 1 9 8 6 ) . Science. 2 3 3 : 3 0 5 . Nishizuka, Y. ( 1 9 8 8 ) . Nature. 3 3 4 : 6 6 1 . , and Nishizuka, Y. ( 1 9 8 8 ) . J. Biol. Chem. 2 6 3 : 6 9 2 7 . , and Nishizuka, Y. ( 1 9 8 7 ) . Science. 2 3 6 : 1 1 1 6 . , and Tanaka, C. ( 1 9 8 8 ) . J. Neurosci. 8 : 3 6 9 . Schlessinger, J. ( 1 9 8 6 ) . J. Cell Biol. 1 0 3 : 2 0 6 7 . 32 Y.

Serotonin treatment produces a n increase in the n u m b e r of varicosities a n d processes w h i c h contact t h e initial s e g m e n t of L7's major neurite. Interestingly, t h e structural c h a n g e s in t h e sensory n e u r o n s also a p p e a r to require t h e presence of the postsynaptic cell, since the serotonin t r e a t m e n t d o e s not a p p e a r to cause g r o w t h of sensory n e u r o n s cultured a l o n e . , N Y ) . Castellucci, K e n n e d y , K a n d e l , a n d G o e l e t have focused o n the m a i n t e n a n c e phase a n d identified four proteins w h o s e rate of synthesis w e r e altered 24 hours after either o n e day or four days of t r a i n i n g ^ .

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