Angiotensin Protocols (Methods in Molecular Medicine) by Donna H. Wang

By Donna H. Wang

Donna Wang and a panel of hands-on specialists describe in step by step aspect all of the significant molecular, biochemical, and practical innovations now utilized in probing the renin-angiotensin procedure. those variety from using embryonic gene concentrating on to create of mutant lines, to the sensible research of parts of the renin-angiotensin procedure. finished and hugely useful, Angiotensin Protocols interprets professional wisdom into without difficulty reproducible equipment that let all biomedical investigators effectively to discover the function of angiotensin in well-being and ailment at the present time.

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24. , et al. (1999) Blocking angiotensin II ameliorates proteinuria and glomerular lesions in progressive mesangioproliferative glomerulonephritis. Kidney Int. 55, 877–889. 25. , Ziyadeh, F. , and Stahl, R. A. (1996) Angiotensin II is mitogenic for cultured rat glomerular endothelial cells. Hypertension 27, 897–905. 26. Weiss, R. H. and Ramirez, A. (1998) TGF-beta- and angiotensin-II-induced mesangial matrix protein secretion is mediated by protein kinase C. Nephrol. Dialysis Transplant. 13, 2804–2813.

Craven, T. , and Redding, J. F. (1991) Evolution of renal insufficiency in ischemic nephropathy. Ann. Surg. 213, 446–456. 6. Davies, D. F. and Shock, N. W. (1950) Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males. J. Clin. Invest. 29, 496. 7. Lindeman, R. , Tobin, J. , and Shock, N. W. (1984) Association between blood pressure and the rate of decline in renal function with age. Kidney Int. 26, 861–868. Three Angiotensin Paradigms in One Patient 35 8.

Am. J. Physiol. 232, F538–F544. 45. Kimbrough, H. , Vaughn, E. , Carey, R. , and Ayers, C. R. (1977) Effect of intrarenal angiotensin II blockade on renal function in conscious dogs. Circ. Res. 40, 174–178. 46. Hall, J. , Guyton, A. , Smith, M. , and Coleman, T. G. (1980) Blood pressure and renal function during chronic changes in sodium intake: role of angiotensin. Am. J. Physiol. 239, F271–F280. 47. Harris, P. J. and Young, J. A. (1977) Dose-dependent stimulation and inhibition of proximal tubular sodium reabsorption by angiotensin II in the rat kidney.

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