Advances in pulmonary drug delivery by Philip Chi Lip Kwok, Hak-Kim Chan

By Philip Chi Lip Kwok, Hak-Kim Chan

The breathing tract has been used to convey biologically lively chemical compounds into the human physique for hundreds of years. in spite of the fact that, the lungs are complicated of their anatomy and body structure, which poses demanding situations to drug supply. Inhaled formulations are in general extra refined than these for oral and parenteral management. Pulmonary drug improvement is consequently a hugely really good region due to its many exact concerns and demanding situations. swift development is being made and gives novel suggestions to current remedy difficulties. Advances in Pulmonary Drug Delivery highlights the most recent advancements during this field.

Show description

Read Online or Download Advances in pulmonary drug delivery PDF

Similar pharmacy books

Capillary Electrophoresis in Chiral Analysis

Capillary Electrophoresis in Chiral research Bezhan Chankvetadze Tbilisi nation college, Republic of Georgia the appliance of capillary electrophoresis (CE) to the sector of chiral research has exploded lately. some great benefits of capillary electrophoresis - super excessive height potency, very good compatibility with organic samples, brief research time, simplicity, versatility and coffee expense - are ideal for the actual size of optical purity, more and more vital within the regulation-ruled pharmaceutical undefined.

Recent Advances in Redox Active Plant and Microbial Products: From Basic Chemistry to Widespread Applications in Medicine and Agriculture

Nature endows us with a treasure chest of eco-friendly Gold filled with extraordinary ‘redox-active’ ingredients which intervene with a variety of organic techniques in our personal physique, in animals, micro organism, fungi and crops. when such traditional items are throughout and in addition in us, we nonetheless don't absolutely know how those compounds really paintings.

Oxford Handbook of Clinical Pharmacy

Now totally up to date for a moment version, the Oxford guide of scientific Pharmacy continues to be the indispensible consultant to medical pharmacy, supplying all of the info wanted for working towards and pupil pharmacists. providing convenient functional tips in a quick-reference, bullet-point layout, it is going to provide the data and self assurance you must offer a medical pharmacy provider.

Handbook of polymers for pharmaceutical technologies. Volume 4, Bioactive and compatible synthetic/hybrid polymers

Polymers are essentially the most interesting fabrics of the current period discovering their purposes in nearly each elements of lifestyles. Polymers are both at once on hand in nature or are chemically synthesized and used based upon the unique functions. Advances in polymer technological know-how and the advent of recent polymers have ended in the numerous improvement of polymers with distinct houses.

Extra info for Advances in pulmonary drug delivery

Sample text

1 Schematic illustrates steps involved in the delivery of siRNA into the lungs� (Reproduced from Lam, J�K�-W� et al�, Adv. Drug Deliv.

Drug Deliv.

Patton and Samantha R. 1 Examples of siRNA-Based Therapeutics in Clinical Trials for Lung Diseases Product Name ALN-RSV01 Excellair™ Delivery Agent/ Route of Administration Naked siRNA/ intranasal Unknown/inhalation Latest Development Status Indication Sponsor RSV infection Alnylam pharmaceuticals Zabecor pharmaceuticals Asthma IIb (completed) II BARRIERS TO siRNA DELIVERY TO THE LUNG As illustrated in Figure 3�1, there are generally five steps that siRNA go through when administered via pulmonary route� Although local delivery of siRNA could obviate the need for targeting and the interaction with serum nuclease to minimize degradation, the lung itself possesses some intrinsic anatomic, physiologic, immunologic, and metabolic hurdles for efficient siRNA delivery� The specific barriers to lung 1.

Download PDF sample

Rated 4.54 of 5 – based on 16 votes